Nigel "Numbuh One" Uno / Hoagie Pennywhistle "Numbuh Two" Gilligan Jr. / D.C.F.D.T.L. (Voice)

Kuki "Numbuh Three" Sanban (Voice)

Wallaby "Numbuh Four" Beatles / D.C.F.D.T.L. / Chip / Toiletnator / Mr. Fibb (Voice)

Abigail "Numbuh Five" Lincoln / D.C.F.D.T.L. (Voice)

Father (Voice)

Adult Hoagie

Adult Kuki

Mr. Boss (Voice)

Computer / Mrs. Uno / Numbuh 86 / Numbuh 363 (Voice)

Stickybeard (Voice)

Sonia / Lee (Voice)

Mr. Dink / Knightbrace (Voice)

Numbuh 362 (Voice)

Mr. Uno (uncredited) (Voice)

Lydia Gilligan (Voice)

Nick (Voice)

Count Spankulot (Voice)

Robin Food (Voice)

Cheese Shogun Roquefort (Voice)

Numbuh 74.239 (Voice)

Adult Numbuh 4