Garfield (voice)

Jon Arbuckle/ Caveman #1 / Junior / Soldier / Computer (voice)

Odie / Jester / Scientist #1 / Cave Cat Narrator (voice)

Chloe / Sara (voice)

Luigi / Black Bart (voice)

George Frideric Handel / Larry (voice)

Little Sara (voice)

Garfield's Mother / Sara's Mother (voice)

Older Sara (voice)

Commander Mendelson (voice)

God (voice)

Additional Voices (voice)